From 1995 - 2008 Professor Gittoes pursued a successful academic career.

In 2008 he moved to the NHS to take on a senior leadership role. He continues to be highly active in research and teaching.

Since 2016 and his appointment as Honorary Professor of Endocrinology, he has also been Head of the Centre for Endocrinology, Diabetes and Metabolism in the Institute of Metabolsim and Systems Research at the University of Birmingham. 

Some of his academic achievements are highlighted below.

Peer reviewed publications

• Tahani N, Choudhary S, Boivin C, Dawson C, Gittoes N, Geberhiwot T. Very high bone mineral density in a monogenic form of obesity-associated insulin resistance. Bone. 2021 Feb;143:115756. doi: 10.1016/j.bone.2020.115756. Epub 2020 Nov 14. PMID: 33197640
• Paskins Z, Crawford-Manning F, Cottrell E, Corp N, Wright J, Jinks C, Bishop S, Doyle A, Ong T, Gittoes N, Leonardi-Bee J, Langley T, Horne R, Sahota O. Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis. BMJ Open. 2020 Nov 3;10(11):e040634. doi: 10.1136/bmjopen-2020-040634. PMID: 33148763 Free PMC article.
• Davis S, Simpson E, Hamilton J, James MM, Rawdin A, Wong R, Goka E, Gittoes N, Selby P. Denosumab, raloxifene, romosozumab and teriparatide to prevent osteoporotic fragility fractures: a systematic review and economic evaluation. Health Technol Assess. 2020 Jun;24(29):1-314. doi: 10.3310/hta24290. PMID: 32588816 Free PMC article.PMID: 33197640The cost-effectiveness of screening in the community to reduce osteoporotic fractures in older women: economic evaluation of the SCOOP study.
• Gittoes NJ, Criseno S, Appelman-Dijkstra NM, Bollerslev J, Canalis E, Rejnmark L, Hassan-Smith Z ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of calcium metabolic disorders and osteoporosis. Eur J Endocrinol. 2020 Aug;183(2):G57-G65. doi: 10.1530/EJE-20-0385.PMID: 32396134 Free PMC article.
• Söreskog E, Borgström F, Shepstone L, Clarke S, Cooper C, Harvey I, Harvey NC, Howe A, Johansson H, Marshall T, O'Neill TW, Peters TJ, Redmond NM, Turner D, Holland R, McCloskey E, Kanis JA; SCOOP study team. Long-term cost-effectiveness of screening for fracture risk in a UK primary care setting: the SCOOP study. Osteoporos Int. 2020 Aug;31(8):1499-1506. doi: 10.1007/s00198-020-05372-6. Epub 2020 Apr 1. PMID: 32239237 Free PMC article. Clinical Trial.
• Welford AE, Lanham-New S, Lord J, Doyle A, Robinson J, Nightingale P, Gittoes N, Greig CA. Influence of combined vitamin D3 supplementation and resistance exercise training on musculoskeletal health in older men and women (EXVITD): protocol for a randomised controlled trial. BMJ Open. 2020 Mar 18;10(3):e033824. doi: 10.1136/bmjopen-2019-033824. PMID: 32193264 Free PMC article.
• Lithgow K, Siqueira I, Senthil L, Chew HS, Chavda SV, Ayuk J, Toogood A, Gittoes N, Matthews T, Batra R, Meade S, Sanghera P, Khan N, Ahmed S, Paluzzi A, Tsermoulas G, Karavitaki N. Pituitary metastases: presentation and outcomes from a pituitary center over the last decade. Pituitary. 2020 Jun;23(3):258-265. doi: 10.1007/s11102-020-01034-2.PMID: 32189207 Free PMC article.
• Al Saleh Y, Beshyah SA, Hussein W, Almadani A, Hassoun A, Al Mamari A, Ba-Essa E, Al-Dhafiri E, Hassanein M, Fouda MA, Al Ali N, Aljohani N, Al-Sayed N, Gittoes N, Elhadd T, Al-Baker W, Sabico S, Al-Daghri N. Diagnosis and management of vitamin D deficiency in the Gulf Cooperative Council (GCC) countries: an expert consensus summary statement from the GCC vitamin D advisory board. Arch Osteoporos. 2020 Mar 2;15(1):35. doi: 10.1007/s11657-020-0709-8. PMID: 32124080
• Condurache CI, Chiu S, Chotiyarnwong P, Johansson H, Shepstone L, Lenaghan E, Cooper C, Clarke S, Khioe RFS, Fordham R, Gittoes N, Harvey I, Harvey NC, Heawood A, Holland R, Howe A, Kanis JA, Marshall T, O'Neill TW, Peters TJ, Redmond NM, Torgerson D, Turner D, McCloskey E; SCOOP Study Team. Screening for high hip fracture risk does not impact on falls risk: a post hoc analysis from the SCOOP study. Osteoporos Int. 2020 Mar;31(3):457-464. doi: 10.1007/s00198-019-05270-6. Epub 2020 Jan 20. PMID: 31960099
• Simpson EL, Martyn-St James M, Hamilton J, Wong R, Gittoes N, Selby P, Davis S. Clinical effectiveness of denosumab, raloxifene, romosozumab, and teriparatide for the prevention of osteoporotic fragility fractures: A systematic review and network meta-analysis. Bone. 2020 Jan;130:115081. doi: 10.1016/j.bone.2019.115081. Epub 2019 Oct 15. PMID: 31626995
• Parsons CM, Harvey N, Shepstone L, Kanis JA, Lenaghan E, Clarke S, Fordham R, Gittoes N, Harvey I, Holland R, Redmond NM, Howe A, Marshall T, Peters TJ, Torgerson D, O'Neill TW, McCloskey E, Cooper C; SCOOP Trial Group. Systematic screening using FRAX® leads to increased use of, and adherence to, anti-osteoporosis medications: an analysis of the UK SCOOP trial. Osteoporos Int. 2020 Jan;31(1):67-75. doi: 10.1007/s00198-019-05142-z. Epub 2019 Oct 12. PMID: 31606826 Free PMC article. Clinical Trial.
• Crowe FL, Thayakaran R, Gittoes N, Hewison M, Thomas GN, Scragg R, Nirantharakumar K. Non-linear associations of 25-hydroxyvitamin D concentrations with risk of cardiovascular disease and all-cause mortality: Results from The Health Improvement Network (THIN) database. J Steroid Biochem Mol Biol. 2019 Dec;195:105480. doi: 10.1016/j.jsbmb.2019.105480. Epub 2019 Sep 18. PMID: 31541727
• Crowe FL, Jolly K, MacArthur C, Manaseki-Holland S, Gittoes N, Hewison M, Scragg R, Nirantharakumar K. Trends in the incidence of testing for vitamin D deficiency in primary care in the UK: a retrospective analysis of The Health Improvement Network (THIN), 2005-2015. BMJ Open. 2019 Jun 4;9(6):e028355. doi: 10.1136/bmjopen-2018-028355.PMID: 31167871 Free PMC article.
• Vitamin D Supplementation and Prevention of Type 2 Diabetes. Hassan-Smith Z, Hewison M, Gittoes N. N Engl J Med. 2019 Oct 31;381(18):1784-1785. doi: 10.1056/NEJMc1912185. PMID: 31665588 No abstract available.
• Faloon S, Venkataraman H, Skordilis K, Griffiths EA, Gittoes NJ, Hassan-Smith ZK, Ayuk J. Lesson of the month 2: Blunt abdominal trauma: atypical presentation of phaeochromocytoma. Clin Med (Lond). 2018 Aug;18(4):345-347. doi: 10.7861/clinmedicine.18-4-345. PMID: 30072564 Free PMC article.
• Santharam S, Fountas A, Tampourlou M, Arlt W, Ayuk J, Gittoes N, Toogood A, Karavitaki N. Impact of menopause on outcomes in prolactinomas after dopamine agonist treatment withdrawal. Clin Endocrinol (Oxf). 2018 Sep;89(3):346-353. doi: 10.1111/cen.13765. Epub 2018 Jul 6. PMID: 29894000
• Fountas A, Chai ST, Ayuk J, Gittoes N, Chavda S, Karavitaki N. A rare challenging case of co-existent craniopharyngioma, acromegaly and squamous cell lung cancer. Endocrinol Diabetes Metab Case Rep. 2018 Mar 28;2018:18-0018. doi: 10.1530/EDM-18-0018. eCollection 2018.PMID: 29623208 Free PMC article.
• McCloskey E, Johansson H, Harvey NC, Shepstone L, Lenaghan E, Fordham R, Harvey I, Howe A, Cooper C, Clarke S, Gittoes N, Heawood A, Holland R, Marshall T, O'Neill TW, Peters TJ, Redmond N, Torgerson D, Kanis JA; SCOOP Study Team. Management of Patients With High Baseline Hip Fracture Risk by FRAX Reduces Hip Fractures-A Post Hoc Analysis of the SCOOP Study. J Bone Miner Res. 2018 Jun;33(6):1020-1026. doi: 10.1002/jbmr.3411. Epub 2018 Mar 23. PMID: 29480960 Free PMC article.
• Turner DA, Khioe RFS, Shepstone L, Lenaghan E, Cooper C, Gittoes N, Harvey NC, Holland R, Howe A, McCloskey E, O'Neill TW, Torgerson D, Fordham R; SCOOP Study Team. The Cost-Effectiveness of Screening in the Community to Reduce Osteoporotic Fractures in Older Women in the UK: Economic Evaluation of the SCOOP Study. J Bone Miner Res. 2018 May;33(5):845-851. doi: 10.1002/jbmr.3381. Epub 2018 Feb 22. PMID: 29470854 Free PMC article. Clinical Trial.
• Shepstone L, Lenaghan E, Cooper C, Clarke S, Fong-Soe-Khioe R, Fordham R, Gittoes NJ, Harvey I, Harvey N, Heawood A, Holland R, Howe A, Kanis J, Marshall T, O’Neill T, Peters T, Redmond N, Torgerson D, Turner D, McCloskey E; for the SCOOP Study Team* Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial. Lancet. 2017 Dec 15. pii: S0140-6736(17)32640-5. doi: 10.1016/S0140-6736(17)32640-5. [Epub ahead of print] PMID: 29254858
• Santharam S, Tampourlou M, Arlt W, Ayuk J, Gittoes NJ, Toogood A, Webster R, Karavitaki N. Prolactinomas diagnosed in the postmenopausal period: clinical phenotype and outcomes. Clinical Endocrinology (Oxf). 2017 Jun 19. doi: 10.1111/cen.13399. [Epub ahead of print] PMID: 28626987 
• Compston J, Cooper A, Cooper C, Gittoes NJ, Gregson C, Harvey N, Hope S, Kanis JA, McCloskey EV, Poole KES, Reid DM, Selby P, Thompson F, Thurston A, Vine N, UK clinical guideline for the prevention and treatment of osteoporosis. National Osteoporosis Guideline Group (NOGG). Archives of Osteoporosis, 2017 Dec;12(1):43. doi: 10.1007/s11657-017-0324-5. Epub 2017 Apr 19. PMID: 28425085
• Tampourlou M*, Ntali G*, Ahmed S, Arlt W, Ayuk J, Byrne JV, Chavda S, Cudlip S, Gittoes NJ, Grossman A, Mitchell R, O’ Reilly M, Paluzzi A, Toogood A, Wass JAH, Karavitaki N, The outcome of patients with regrown non-functioning pituitary adenoma after primary treatment - further tumour progression and risk factors: a retrospective cohort study from two large UK specialist centres. Journal of Clinical Endocrinology and Metabolism, 2017 Mar 2. doi: 10.1210/jc.2016-4061. [Epub ahead of print] PMID: 28323946.
• Gittoes OM, Gittoes NJ, Breathlessness and neck swelling after a rugby game. British Medical Journal. 2017 Feb 2;356:j311. doi: 10.1136/bmj.j311. PMID: 28154129​
• Hassan-Smith Z, Gittoes NJL, Hewison M. 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression. PLOS ONE, IN PRESS.
• Harborne K, Hazlehurst JM, Shanmugaratnam H, Pearson S, Doyle A, Gittoes NJL, Choudhary S, Crowley RK. Compliance with established guidelines for the radiological reporting of atypical ‎femoral fractures. British Journal of Radiology, 2016 Jan;89(1057):20150443. doi: 10.1259/bjr.20150443. Epub 2015 Oct 28.
• Shipman K, Stammers J, Doyle A, Gittoes NJL. Delivering a quality assured fracture liaison service in a UK teaching hospital - is it achievable? In press Osteoporosis International 2016. May 18. [Epub ahead of print]; PMID: 27193285
• Tampourlou M*, Ntali G*, Ahmed S, Arlt W, Ayuk J, Byrne JV, Chavda S, Cudlip S, Gittoes N, Grossman A, Mitchell R, O’ Reilly M, Paluzzi A, Toogood A, Wass JAH, Karavitaki N, The outcome of patients with regrown non-functioning pituitary adenoma after primary treatment - further tumour progression and risk factors: a retrospective cohort study from two large UK specialist centres. Journal of Clinical Endocrinology and Metabolism, IN PRESS
• Sanderson J, Martyn-St James M, Stevens J, Goka E, Wong R, Campbell F, Stevenson M, Selby P, Gittoes NJ, Davis S. Clinical effectiveness of bisphosphonates for the prevention of fragility fractures: a systematic review and network meta-analysis. Bone 2016. Jun 1. pii: S8756-3282(16)30149-1. doi: 10.1016/j.bone.2016.05.013. [Epub ahead of print]; PMID: 27262775
• O'Reilly MW, Reulen RC, Gupta S, Thompson CA, Dineen R, Goulden EL, Bugg G, Pearce H, Toogood AA, Gittoes NJ, Mitchell R, Thompson CJ, Ayuk J. ACTH and gonadotropin deficiencies predict mortality in patients treated for nonfunctioning pituitary adenoma: long-term follow-up of 519 patients in two large European centres, Clinical Endocrinology (Oxf). 2016 Jun 21.doi:10.1111/cen.13141. [Epub ahead of print] PMID: 27327840
• Chauhan P, Gittoes NJ, Geberhiwot T. Successful treatment of recurrent renal stones with Cinacalcet in a patient with primary hyperparathyroidism. BMJ Case Rep. 2016 Aug 12;2016. pii: bcr2016216311. doi: 10.1136/bcr-2016-216311. PMID: 27520998
• Davis S, Martyn-St James M, Sanderson J, Stevens J, Goka E, Rawdin A, Sadler S, Wong R, Campbell F, Stevenson M, Strong M, Selby P, Gittoes NJ. A systematic review and economic evaluation of bisphosphonates for the prevention of fragility fractures. Health Technology Assessment. 2016 Oct; 20(78):1-406. PMID: 27801641
• Walsh J, Gittoes NJ, Selby P, Society for Endocrinology Clinical Committee. SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of acute hypercalcaemia in adult patients. Endocrine Connections. 2016 Sep;5(5):G9-G11. No abstract available. PMID: 27935816
• Turner J, Gittoes NJ, Selby P; Society for Endocrinology Clinical Committee. SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of acute hypocalcaemia in adult patients. Endocrine Connections. 2016 Sep;5(5):G7-G8. No abstract available. PMID: 27935815
• Tampourlou M*, Ntali G*, Ahmed S, Arlt W, Ayuk J, Byrne JV, Chavda S, Cudlip S, Gittoes N, Grossman A, Mitchell R, O’ Reilly M, Paluzzi A, Toogood A, Wass JAH, Karavitaki N, The outcome of patients with regrown non-functioning pituitary adenoma after primary treatment - further tumour progression and risk factors: a retrospective cohort study from two large UK specialist centres. Journal of Clinical Endocrinology and Metabolism, IN PRESS
• Enclosing a pen reduced time to response to questionnaire mailings. Bell K, Clark L, Fairhurst C, Mitchell N, Lenaghan E, Blacklock J, Cushnaghan J, Cooper C, Gittoes N, O'Neill TW, Shepstone L, Torgerson DJ; SCOOP Study Team. J Clin Epidemiol. 2015 Dec 29. pii: S0895-4356(15)00580-6. doi: 10.1016/j.jclinepi.2015.12.004. [Epub ahead of print]​
• Vitamin D - what is normal according to latest research and how should we deal with it? Gittoes NJ. Clin Med (Lond). 2015 Dec;15 Suppl 6:s54-7. doi: 10.7861/clinmedicine.15-6-s54.
• Compliance with established guidelines for the radiological reporting of atypical femoral fractures. Harborne K, Hazlehurst JM, Shanmugaratnam H, Pearson S, Doyle A, Gittoes NJ, Choudhary S, Crowley RK. Br J Radiol. 2016 Jan;89(1057):20150443. doi: 0.1259/bjr.20150443. Epub 2015 Oct 28.
• Difficult access in the anaesthetic room leads to a difficult diagnosis. Crabtree S, Lowry D, Tiwari A, Gittoes N. BMJ. 2015 Jul 8;351:h3430. doi: 10.1136/bmj.h3430.
• National Osteoporosis Society practical clinical guideline on vitamin D and bone health. Francis RM, Aspray TJ, Bowring CE, Fraser WD, Gittoes NJ, Javaid MK, Macdonald HM, Patel S, Selby PL, Tanna N. Maturitas. 2015 Feb;80(2):119-21. doi: 10.1016/j.maturitas.2014.11.018. Epub 2014 Nov 27.
• Fear of medication side effects is a barrier to optimal osteoporosis care. Sheltawy AA, Criseno S, Gittoes NJ, Crowley RK. Osteoporos Int. 2015 Feb;26(2):843-4. doi: 10.1007/s00198-014-2922-z. Epub 2014 Oct 22.
• National Osteoporosis Society vitamin D guideline summary. Aspray TJ, Bowring C, Fraser W, Gittoes N, Javaid MK, Macdonald H, Patel S, Selby P, Tanna N, Francis RM; National Osteoporosis Society. Age Ageing. 2014 Sep;43(5):592-5. doi: 10.1093/ageing/afu093. Epub 2014 Jul 28.
• Green AE, Sherlock M, Stewart PM, Gittoes NJL, Toogood AA. (2014), Extensive experience in the management of prolctinomas, Clin Endocrinol. Jan 31, EPUB Ahead of Print. PMID 24483350. 
• Manolopoulos KN, West A, Gittoes NJL. (2013), The paradox of prevention--bilateral atypical subtrochanteric fractures due to bisphosphonates in osteogenesis imperfecta, J Clin Endocrinol Metab. 2013 Mar;98(3):871-2.
• Shepstone L, Fordham R, Lenaghan E, Harvey I, Cooper C, Gittoes NJL, Heawood A, Peters T, O'Neill T, Torgerson D, Holland R, Howe A, Marshall T, Kanis J, McCloskey E. (2012) A pragmatic randomised controlled trial of the effectiveness of screening older women for the prevention of fractures: rationale, design and methods for the SCOOP study, Osteoporos Int. 2012 Oct;23(10):2507-15.
• Patel P, Hardy R, Sumathi V, Bartle G, Kindblom L-G, Grimer R, Bujalska I, Stewart PM, Rabbitt E, Gittoes NJL, Cooper MS. (2012) Expression of 11b-Hydroxysteroid Dehydrogenase Enzymes in Human Osteosarcoma: Potential Role in Pathogenesis and
as Targets for Treatments, Endocrine Related Cancer, 19 (4), 589-598.
• Nirmalan A, Anderson M, Ferner RE, Gittoes NJL. (2011) Hypomagneseamia and seizures. Clinical Medicine, 11 (6), 591-593.
• Harries A, Gittoes NJL, Mitchell R. (2010) Resolution of 3rd nerve
palsy following treatment of prolactinoma with cabergoline. Acta Neurochirurgica, 152, 1741-1743.
• Crabtree NJ, Bebbington NA, Chapman DM, Wahid YS, Ayuk J, Boivin CM, Cooper MS, Gittoes NJL. (2010) Impact of UK National guidelines based on FRAX® - Comparison with current clinical practice. Clinical Endocrinology, 73, 452-456.
• Mukhopadhyay R, Strens LH, Winer JB, Ayuk JA, Gittoes NJL. (2010)
Having the vision to measure calcium. Journal of Neurology, Jun, 257 (6), 1032-4.
• Langston AL, Campbell MK, Fraser WD, MacLennan GS, Selby PL, Ralston SH; PRISM Trial Group. (2010) Randomized trial of intensive bisphosphonate treatment versus symptomatic management in Paget's disease of bone. Journal of Bone and Mineral Research, 25(1), 20-31.

​

Review articles

• Aojula N, Khan S, Gittoes N, Hassan-Smith Z. Normocalcaemic primary hyperparathyroidism: what is the role of parathyroid surgery? Ther Adv Endocrinol Metab. 2021 Feb 27; 12:2042018821995370. doi: 10.1177/2042018821995370. eCollection 2021. PMID: 33717430 Free PMC article. Review.
• Aojula N, Ready A, Gittoes N, Hassan-Smith Z. Management of Parathyroid Disease during the COVID-19 Pandemic. J Clin Med. 2021 Feb 26;10(5):920. doi: 10.3390/jcm10050920. PMID: 33652905 Free PMC article. Review.
• Eggermann T, Elbracht M, Kurth I, Juul A, Johannsen TH, Netchine I, Mastorakos G, Johannsson G, Musholt TJ, Zenker M, Prawitt D, Pereira AM, Hiort O; Genetic testing in inherited endocrine disorders: joint position paper of the European reference network on rare endocrine conditions (Endo-ERN). European Reference Network on Rare Endocrine Conditions (ENDO-ERN. Orphanet J Rare Dis. 2020 Jun 8;15(1):144. doi: 10.1186/s13023-020-01420-w. PMID: 32513286 Free PMC article. Review.
• de Bray A, Tomas J, Gittoes N, Hassan-Smith Z. Management of endocrine conditions at the end of life. Br J Hosp Med (Lond). 2020 May 2;81(5):1-9. doi: 10.12968/hmed.2020.0096. Epub 2020 May 23. PMID: 32468945 Review.
• Turner J, Gittoes N, Selby P; Society for Endocrinology Clinical Committee. SOCIETY FOR ENDOCRINOLOGY EMERGENCY ENDOCRINE GUIDANCE: Emergency management of acute hypocalcaemia in adult patients. Endocr Connect. 2019 Jun 1;8(6):X1. doi: 10.1530/EC-16-0056. PMID: 32022081 Free PMC article. 
• Hassan-Smith & Gittoes NJL. (2017) Hypocalcaemia, Medicine, IN PRESS.
• Shipman KE, Doyle A, Arden H, Jones T, Gittoes NJ. (2017) Development of fracture liaison services: What have we learned? Injury. 2017 Sep 1. pii: S0020-1383(17)30549-1. doi: 10.1016/j.injury.2017.08.030. [Epub ahead of print]
• Gittoes NJ. (2017) Progress and problems in bone and mineral disorders. European Endocrinology. 2017; 13(1):19-20.
• Kanis JA, Compston J, Thurston A, Cooper C, Gittoes NJ, Gregson C, Harvey N, Hope S, McCloskey E, Poole K, Reid D, Selby P, Thompson F, Vine N. (2017) UK clinical guideline for the prevention and treatment of osteoporosis. Archives in Osteoporosis. 2017 Dec;12(1):43. doi: 10.1007/s11657-017-0324-5. Epub 2017 Apr 19. PMID: 28425085
• Mild primary hyperparathyroidism-to treat or not to treat? Hassan-Smith ZK, Criseno S, Gittoes NJL. Br Med Bull. 2019 Mar 1;129(1):53-67. doi: 10.1093/bmb/ldy042. PMID: 30576424 Review.
• Hassan-Smith Z, Hewison M, Gittoes NJ. (2017) Effect of vitmain D deficiency in developed countries. British Medical Bulletin, 2017 Mar 9:1-11. doi: 10.1093/bmb/ldx005. [Epub ahead of print]. https://doi.org/10.1093/bmb/ldx005
• Jahagirdar V, Gittoes NJ. (2017) Diabetes and bone health. Diabetes & Primary Care Australia, 2(2), 1-8.
• Turner J, Gittoes NJ, Selby P. (2016) SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of acute hypocalcaemia in adult patients; Society for Endocrinology Clinical Committee. Endocrine Connections, 2016 Sep;5(5):G7-G8. PMID: 27935815
• Walsh J, Gittoes NJ, Selby P. (2016) SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of acute hypercalcaemia in adult patients; Society for Endocrinology Clinical Committee. Endocrine Connections, 2016 Sep;5(5):G9-G11. PMID: 27935816.
• Jahagirdar V, Gittoes NJ. (2016) Diabetes and bone health. Diabetes & Primary Care, 5(2), 23-31.
• May C, Gittoes NJ, Cole T. (2016) Genomics in mainstream endocrinology. The Endocrinologist 120, Summer, 18
• Gittoes NJ. (2016). Vitamin D - what is normal according to latest research and how should we deal with it? Clinical Medicine (Lond), 16(2), 171-4. doi: 10.7861/clinmedicine.16-2-171.
• Crowley R, Gittoes NJL. (In Press) Clinical Question: Elevated PTH with normal serum calcium level: a structured approach. Clinical Endocrinology (Oxf). 2016 Mar 4. doi: 10.1111/cen.13056. [Epub ahead of print]
• Gittoes NJL (2015). Vitamin D – what is normal according to latest research and how should we deal with it? Clinical Medicine, 15(6), s54-s57.
• Davis S, Martyn-St James M, Sanderson J, Stevens J, Goka E, Rawdin A, Sadler S, Wong R, Campbell F, Stevenson M, Strong M, Selby P, Gittoes NJ. (2015) Technology Assessment Report commissioned by the NIHR HTA Programme on behalf of the National Institute for Health and Care Excellence. Bisphosphonates for preventing osteoporotic fragility fractures (including a partial update of NICE technology appraisal guidance 160 and 161). Technology Assessment Report: Final report to the National Institute for Health and Care 
• Gittoes NJ, Paskins Z. (2015) Peer review of osteoporosis services – impetus for change, Osteoporosis Review, Spring.
• Gittoes NJL, Cooper A. (2015) Dilemmas in the management of osteoporosis, Drug and Therapeutics Bulletin, 53(2) February, 18-24.
• Gittoes NJ. (2014) Value of peer review of service, Osteoporosis Review, Spring.
• Crowley R, Gittoes NJL (2014) When would I use medical therapies for the treatment of primary hyperparathyroidism? Clin Endocrinol (Oxf). 2013 Dec;79(6):770-3.
• Ayuk JA, Gittoes NJL. (2014) Contemporary View of the Clinical Relevance of Magnesium Homeostasis, Annals of Clinical Biochemistry, Am J Kidney Dis. 2014 Apr;63(4):691-5.
• Crowley R, Gittoes NJL. (2013) How to approach hypercalcaemia, Clin Med. Jun;13(3):287-90. 
• Ayuk JA, Gittoes NJL. (2011) How should hypomagnesaemia be investigated and treated? Clinical Endocrinology 75 (6), 743-746.
• Ayuk JA, Cooper MS, Gittoes NJL. (2010) New Perspectives in the Management of Primary hyperparathyroidism, Therapeutic Advances in Endocrinology and Metabolism 1 (5), 197-206.
• Cooper MS, Gittoes NJL. (2010) Bone health and thyroid disease, Osteoporosis
Review, 18 (4), 1-7.
• Gittoes NJL, Cooper MS. (2010) Bone as an endocrine organ, Osteoporosis Review 18 (3), 20-23.
• Cooper MS, Gittoes NJL. (2010) Primary hyperparathyroidism – Is mild disease worth treating? Clinical Medicine 10 (1), 45-49.
• ToozeA, Gittoes NJL, Jones CA, Toogood AA. (2009) Neurocognitive consequences of surgery and radiotherapy for tumours of the pituitary, Clinical Endocrinology 70
(4), 503-511.
• Cooper MS, Gittoes NJL. (2008) Diagnosis and Management of Hypocalcaemia, British Medical Journal 336 (7656), 1298-1302.

Chapters in books

• Gittoes NJL. (2020) Calcium & Bone Metabolism, Section editor and reviewer, In: Oxford Handbook of Endocrinology and Diabetes, 4th edition, eds., Wass JAH, Turner HE, Oxford University Press, Oxford.
• Gittoes NJL. (2018) Hypocalcaemia, In: Oxford Desktop Reference, eds., Turner, Eastell R, Grossman, Oxford University Press, Oxford.
• Ayuk JA, Gittoes NJL. (2018) Management of Hyperparathyroidism, In: Otorhinolaryngology and Head and Neck Surgery, eds., Watkinson JA, Clark R, Scott Brown, Chapter 73.
• Gittoes NJL. (2016) Vitamin D – What is normal according to latest research and what should we do about it? Horizons in Medicine, 2016.
• Gittoes NJL. (2014) Calcium & Bone Metabolism, Section editor and reviewer, In: Oxford Handbook of Endocrinology and Diabetes, 3rd edition, eds., Wass JAH, Turner HE, Oxford University Press, Oxford.
• Cooper MS, Gittoes NJL. (2013) Hypocalcaemia, In: Tarascon Adult Endocrinology Pocketbook, eds., Laufgraben M, Gopalakrishnan G, Jones & Bartlett Learning, Sudbury, MA.
• Ayuk JA, McCabe CJ, Gittoes NJL. (2011) Pituitary Carcinoma. In: Oxford Textbook of Endocrinology and Diabetes, 2nd ed., Oxford University Press, Oxford.
• Gittoes NJL, Ayuk J and Ferner R. (2011) Diabetes Secondary to Drug Therapy. In: Textbook of Diabetes, 4th Edition, eds., Holt R, Flyvjberg A, Goldstein B, Cockram C, Wiley-Blackwell, Scientific Publications, London.
• Kim D, Gittoes NJL. (2011) Endocrine Disease: Molecular Biology and Genetic Testing. In: Textbook of Head and Neck Surgery and Oncology, 5th edition, eds., Watkinson JC, Gilbert R, Stell and Maran's.

Major Grants and Research Studies

1. Thyroid hormone receptor expression and function in "non-functioning" pituitary tumours. Medical Research Council, Career Establishment Grant, £310 305, 1998 (5 years).

2. Pretranslational expression of nuclear steroid receptors and pituitary tumour transforming gene (PTTG) in human pituitary adenomas. Medical Research Council, Equipment Grant for £73 368, 1999.

3. Pre-receptor regulation of glucocorticoids and the control of pituitary cell proliferation: a novel target for tumour therapy. The United Birmingham Hospitals Endowment Fund grant for post-doctoral fellow, £59 979, 2001 (2 years). Extension 5 months £11,044.

4. Pre-receptor metabolism and the control of hormone action. Medical Research Council Cooperative Group Grant, £345 982 2002 (5 years)

5. Pituitary radiotherapy as a risk factor for cerebrovascular disease and neurocognitive
dysfunction. The United Birmingham Hospitals Endowment Fund grant for post-doctoral fellow, £49 959, 2004 (2 years)

6. Genetics service for patients in primary and secondary care (endocrinology section). Department of Health, Funds for staff and service development, £1 800 000, 2004

7. A pragmatic randomised controlled trial of screening for osteoporosis in older women. Medical Research Council Health Technology Assessment grant, £4 280 273 + £4 750 985 NHS costs, 2006 (7 years)

8. Osteoporosis and growth hormone nurse salary support, Eli Lilly, £37 607, 2007 (1 year)

9. The role of intracellular glucocorticoid metabolism in osteosarcoma pathogenesis. The United Birmingham Hospitals Endowment Fund grant for technician, £49 732, 2007 (2 years)

10. Osteogenesis imperfecta: surveys of disease complications and the effects of treatment. The United Birmingham Hospitals Endowment Fund grant for research nurse, £69 589, 2011 (2 years)

11. Understanding the molecular mechanism of bone disease in Gaucher patients. Shire Pharmaceuticals funding for Clinical Research Fellow, £195,000, 2012, (3 years)

12. Phase II study of the impact of a selective 11beta-HSD1 inhibitor on biochemical
markers of bone turnover in post-menopausal osteopaenia, MRC-AZ, £360,000, 2013, (2 years)

13. PhD studentship 3 years – “Influence of combined vitamin D supplementation and resistance exercise training on musculoskeletal health in frail older men and women (EXVITD)”, National Osteoporosis Society, £94,000, 2015 (3 years)

14. The BLAST OFF (Bisphosphonate aLternAtive regimenS for the prevenTion of Osteoporotic Fragility Fractures) Study – The study will look at how effective different bisphosphonate regimens are compared to Alendronate at preventing fractures, whether the reduction in fracture risk can be achieved at a reasonable financial cost and to establish the acceptability of different approaches to patients. NIHR HTA Reference Number: NIHR127550, c£400,000, 2019 (3 years)

15. A Randomized, Double-blind, Placebo-controlled, Adaptive Study to Evaluate Symptom Improvement and Metabolic Control Among Adult Subjects With Symptomatic Hypoparathyroidism Treated With Recombinant Human Parathyroid Hormone [rhPTH(1-84)]. Shire Pharmaceuticals, 2020-21

16. Randomised Trial of Teriparatide followed by Zoledronic Acid versus standard care to prevent fractures in adults with Osteogenesis Imperfecta (TOPaZ). Efficacy and Mechanism Evaluation and Eli Lilly, MRC, 2019-2022

Recently Invited Talks 

2021

• American Endocrine Society annual meeting, San Francisco/virtual, 03/2021, Meet the Professor; Challenging cases in bone and mineral
• Regional Endocrine Meeting, Bristol 10/2021, Lecture; Vitamin D and mineral
• BAETS/RCSEd annual thyroid and parathyroid masterclass 2021, Virtual, 03/2021, Lecture; Parathyroid endocrinology - what should a surgeon know?

2020

• Paediatric Metabolic Bone Group, Birmingham, 03/2020, Lecture; Adult bone diseases for paediatricians
• American Endocrine Society annual meeting, San Francisco, 03/2020, Meet the Professor; Challenging cases in bone and mineral
• Royal College of Physicians, Medicine 2020 Annual Conference, Birmingham, 04/2020, Lecture, NICE Guideline on primary hyperparathyroidism
• Scottish Osteoporosis Group, Glasgow, 05/2020, Lecture; Fracture Liaison Services, why standards are important
• Endocrinology Academy Meeting, London, 07/2020, Lecture; Physiology, biochemistry and imaging of calcium disorders
• IAMICON Webinar series to Indian subcontinent, 10/2020, Lecture; Optimal contemporary management of osteoporosis
• Royal College of Physicians, Glasgow, 11/2020, Lecture; Acute calcium problems
• British Endocrine Societies Annual Meeting, Virtual, 11/2020, Lecture; Bone and calcium management through COVID
• Royal Osteoporosis Society National Meeting, Virtual, 12/2020, Workshop; Everyday difficulties in common cases

2019                              

• Association of British Clinical Diabetologists (ABCD) annual meeting, London, 02/2019, Lecture; Bone and calcium disorders in renal disease
• Pulse Live, National GP Training Course, London, 03/2019, Lecture; The role of vitamin D in society
• National Pituitary MDT meeting – Neurosurgery and Endocrinology, RCP, 06/2019, Lecture; The role of the CRG in optimizing pituitary outcomes
• Osteoporosis 2019, MA Healthcare, 06/2019, Lecture; Choosing the right bisphosphonate
• European Society of Endocrinology, Parathyroid Expert Meeting, Amsterdam, 06/2019, Lecture; NICE Guideline on primary hyperparathyroidism
• International Birmingham Pituitary Preceptorship, 09/2019, Lecture; Pituitary disease and bone
• Oxford Endocrinology Masterclass, Oxford, 09/2019, Lecture; Clinical care of hypocalcaemia
• Oxford Endocrinology Masterclass, Oxford, 09/2019, Lecture; Practical management of hypercalcaemia
• British Society of Rheumatology, 10/2019, Lecture; Secondary causes of osteoporosis
• British Endocrine Societies Annual Meeting, Society for Endocrinology, Brighton, 11/2019, Lecture; Surgical intervention for parathyroid disease
• British Endocrine Societies Annual Meeting, Society for Endocrinology, Brighton, 11/2019, Lecture; Challenges in recurrent hyperparathyroidism
• British Endocrine Societies Annual Meeting, Society for Endocrinology, Brighton, 11/2019, Lecture; What can the CRG bring to quality development in endocrinology nationally
• Wessex Endocrine Society, Annual Meeting, Southampton, 11/2019, Lecture; NICE Guidelines on Primary Hyperparathyroidism
• Hammersmith Endocrine Course, London, 12/2019, Lecture; Delivering on the NICE primary hyperparathyroidism guideline

2018                              

• Royal College of Physicians, Regional Update, Cambridge, 03/2018, Lecture; Osteoporosis management
• Midlands Endocrine and Diabetes Club, 05/2018, Debate; Surgery for mild primary hyperparathyroidism
• European Society of Endocrinology, Symposium on Hypoparathyroidism, 05/2018, Lecture; Hypoparathyroidism – long term outcomes and quality of life
• Royal Society of Medicine, Endocrine Imaging Symposium, 07/2018, Lecture; Applications of bone density 
• General Practitioners Training Day, Bone Research Society, Birmingham, 09/2018, Lecture; Investigating raised calcium in primary care
• 2nd European Symposium on Hypoparathyroidism, 10/2018, Lecture; Defining inadequate control of hypoparathyroidism – results of Delphi panels
• Clinical Osteoporosis Update 2018, Manchester, 10/2018, Workshop; Vitamin D – dilemmas and management

2017                          

• Royal College of Physicians Edinburgh, Diabetes & Endocrinology Symposium, 10/2017, Lecture; How I manage hypocalcaemia
• Royal College of Physicians Update in Endocrinology, London, 09/2017, Lecture; How to treat osteoporosis
• British Society for Rheumatology Annual Conference, Birmingham, 04/2017, Lecture; 5 years on Denosumab: What next?
• Endocrine Nurse Update 2017, Birmingham 03/2017, Workshop; Challenges in managing patients with hypoparathyroidism
• Royal College of Physicians London, Medicine 2017 – RCP Annual Conference, 03/2017, Lecture; Osteoporosis – Who to treat, with what and for how long?

2016                       

• Society for Endocrinology, Annual Conference, Brighton, 11/2016, Lecture; Normocalcaemic hyperparathyroidism – treat or discharge?
• Oxford Endocrinology Masterclass, Disorders of the Thyroid and Bone, Oxford, 09/2016, Lecture; Osteoporosis: the next step in management
• Advanced General Medicine Conference, Royal College of Physicians and Indian Medical Societies, Mumbai, India, 06/2016, Lecture; Metabolic bone diseases and vitamin D deficiency
• British Menopause Society Annual Conference, Royal College of Physicians, London, 05/2016, Lecture; Vitamin D: what's normal and role in osteoporosis prevention